Tag Archives: Italy

When Physicians Give Up: Anna Maria Luisa de’ Medici’s Infant Convulsion Powder

By Ashley Buchanan

Anna Maria Luisa de' Medici
Anna Maria Luisa de’ Medici by Antonio Franchi [Public domain], via Wikimedia Commons
On July 19, 1736, Baroness Massimilianna Moltke wrote Anna Maria Luisa, the Electress Palatine and last Medici princess, to thank her for sending a “miraculous powder” to treat infant convulsions, or “male caduco.” In the letter sent from Vienna to Florence, the Baroness stated that the powder had had extraordinary effects on three children from the most important families of Vienna. She went on to explain that these children had been so violently taken by convulsions that the physicians had “given up on them.” Not only had the powder from “la Serenissima Elettrice” cured the children, the baroness also stated that a number of months had passed and the children remained in perfect health. The baroness concluded her letter by thanking Anna Maria Luisa and assuring the Medici princess that the three most prominent families of Vienna would be eternally grateful and would always remember “Vostra Altezza Elettorale e Serenissima” for her generous gift.

Of the over two hundred culinary, alchemical, and medicinal recipes that Anna Maria Luisa de’ Medici (1667-1743), collected during her life and which are preserved in the Archivio di Stato of Florence, this one recipe for infant convulsions stands out.[1] The recipe called for the precipitated powder of three ounces of human skull from a person who had died violently but had not been buried, two ounces of oriental pearls, and two ounces of red and white coral. These precipitated powders were then combined with one ounce of amber, one ounce of peony root, and one ounce of peony seeds. The recipe then instructed that all the ingredients be pulverized together and passed through a fine sieve.

Once the powder was prepared, the recipe then prescribed giving five grains of it to the afflicted child. Requested by elite men and women in numerous epistolary exchanges, this powder was continually lauded for its extraordinary effects in curing infants of life-threatening convulsions.

The letter of Baroness Moltke is just one of many letters concerning a medicinal remedy that the electress exchanged with Italian and European noblemen and women. Anna Maria Luisa’s recipe for infant convulsion powder and the epistolary exchange that promoted it were part of a system of courtly gift giving which supported the personal and familial strategies of the European nobility. While women could not participate directly in the new court science of experimentation, recipes represented an acceptable means to access, exchange, experiment with, and distribute medical knowledge.  As the letters exchanged between the Medici princess and European nobility show, the infant convulsion powder became a meaningful and lucrative form of social currency in court politics.

The worth of this powder lay in the nature of the victims it reputedly cured. The ability to treat and cure such an ailment that affected the children of elite families garnered great social and political capital. It is no coincidence that the three children Anna Maria Luisa “cured” in Vienna belonged to three of the most important families of that country. By 1737 Anna Maria Luisa’s social and political position was tenuous—she was the last of the Medici line. Born in 1667 in Florence, Anna Maria Luisa was the only daughter and second child of Cosimo III, Grand Duke of Tuscany.  In 1691, she was married to Johann Wilhelm II (1658-1716), Elector Palatine.  She lived in Düsseldorf, her husband’s capital, until his death in 1716. A year later Anna Maria Luisa returned to her native Florence. During Anna Maria Luisa’s twenty-six year absence neither of her brothers, Ferdinando or Gian Gastone (1671–1737), had produced a Medici heir. By 1737 the Medici state would become a Hapsburg satellite, ruled by the Lorraine dynasty.

As a widow and last member of the Medici line, Anna Maria Luisa would have played little significance in the social and political negotiations and familial dynastic strategies of early modern Europe. However, as a source of medical knowledge—via a recipe—and the keeper of a powder that was widely distributed and known to cure infant convulsions, she possessed an important commodity for elite families. Paradoxically, Anna Maria Luisa was able to do for others what she could not do for her own family line: ensure its continuation. By distributing her prized remedy, Anna Maria Luisa created political alliances and interpersonal relationships with important elite families across Europe. Relationships she could call upon as she carried out the difficult tasks of managing the difficult transfer of power to the Lorraine dynasty and ensuring her personal legacy.


[1] A special thanks to the Medici Archive Project whose generous Samuel Freeman Charitable Trust fellowship made this research possible.

Cipriano Piccolpasso’s Recipe for the Transmutation of Matter

By Steve Wharton

Cipriano Piccolpasso, Tav. 20, illustrations associated with the making of ‘lustres’, I Tre Libri Dell’Arte Del Vasajo… (1556-75), Dallo Stabilimento Tipografico, 1857.

Certain recipes can tell us a great deal about the cultural and sometimes the technological contexts within which they were compiled and disseminated. In his mid-sixteenth century Italian treatise, the Three Books of the Art of the Potter.., Cipriano Piccolpasso (1523-79) discussed and illustrated the technology and the manufacturing processes that were central to the making of tin-glazed earthenware pottery.[1] Frequently described as having been produced between the years 1556 and 1558, though revised throughout his lifetime, and as an instruction manual, the manuscript was unpublished until the mid-nineteenth century.[2] Today, it is considered the authentic voice of the sixteenth-century Italian potter. However, as I have discussed elsewhere, Piccolpasso’s descriptions are based on observation of the techniques and processes employed by the potters of Castel Durante, rather than practice. Nevertheless his treatise is consistently and frequently cited in highly technical physical and chemical analyses of Renaissance glaze and related technology.[3] The recipes discussed include those for colour as well as those for ‘ruby’ and ‘gold’ lustres: that is the addition of pristine metallic surfaces to otherwise finished ware. Piccolpasso says of them: ‘…I do not intend to go on further until I have discoursed to you upon gold maiolica, from what I have heard of it from others, not that I have ever made it or even seen it being done. I do know that it is painted over finished wares…’

While Piccolpasso is passing on hearsay, he nevertheless includes a recipe for what he calls Rosso da Maiolica [red maiolica]:

A            B

Red earth                           oz           3             6

Armenian Bole                 oz           1             0

Ferretto of Spain             oz           2             3

Cinnabar                            oz           0             3

to which he adds: ‘…with this last mixture ‘B’, include a calcined silver carlino [a burnt coin]’. In his marginal notes he confirms that ‘…this last mixture “B” is called golden maiolica’.

The inclusion of particularly cinnabar is at first a mystery; it has no function in a recipe such as this. It is only when we know that cinnabar is a compound of mercury and sulphur and that all the ingredients are ground together in a pot of red [i.e. strong] vinegar, one of the ‘sharp waters’ employed by alchemists, that things begin to make a little more sense. During the period, what were described as the ‘arts of fire’, which included the making of pottery, were also used to make not only high status bronze-cast sculpture and gold-cast jewellery, for example, but also to manufacture and prepare more ubiquitous substances such as pigments and other colouring agents for an array of manufacturing techniques. These included easel and fresco painting, tesserae for mosaics, fabric dyes and the decoration of glass and indeed pottery. As has been observed, alchemy, in terms of practical chemistry, was primarily concerned with the making of industrial products by using chemical processes; it was not necessarily concerned with the occult, the mystical or the spiritual.[4]

What Piccolpasso described was and is still known as a ‘transmutation lustre’ [my emphasis] in which a paste based upon raw clay is applied to the surface of a pot. It is a well-known technique: the fifteenth-century Hispano-Moresque potters used a red ochre clay corresponding exactly to that included in this recipe. A silver salt was added, in the form of a calcined carlino, together with a copper compound, known as Ferretto of Spain, to produce ‘gold’ lustre. No gold was ever used and in that sense it is the perception of gold that becomes significant.

The transmutation of base material into gold, however, was central to one of the alchemists’ most important aims, and mercury, sulphur and ‘sharp water’ were all part of the process. In his discussion of this recipe, Piccolpasso may well have been relying on what he knew of the presence of alchemy in all kinds of chemical and physical practice, including the production of gold maiolica. More specifically, he raises the question: to what extent might the potters of north-central Italy, in employing their own art of fire, be considered alchemists? What is more certain is that the philosophy associated with alchemy provides an insight into the ways in which knowledge and what kinds of knowledge were gathered and transmitted during the period. Ultimately, Piccolpasso’s record of what he understood as the recipe for ‘gold’ lustre reflected the endeavours of contemporary scholars and indeed pottery practitioners to cope with the challenges of defining and connecting all the different kinds and parts of knowledge that were circulating at that time.


[1] Piccolpasso, Cipriano, Li tre libri dell’arte del vasaio nei quai si tratta non solo la pratica, ma brevemente tutti gli secreti di essa cosa che persino al dè d’oggi è stata sempre tenuta ascosta…ecc., National Art Library, Victoria and Albert Museum, South Kensington, London, MSL/1861/7446

[2] Caiani, A., 1857, I Tre Libri dell’Arte del Vasajo, Roma, dallo Stabilimento Tipografico, Via del Corso, num. 387.

[3] See, for example, G. Padeletti, G. M. Ingo et al, ‘First-time Observation of Maestro Giorgio Masterpieces by Means of non-destructive Techniques’, Applied Physics. A, Materials Science & Processing, 0947-8396, Padeletti, 2006, vol. 83 issue, 4, pp. 475-483; B. Brunetti et al., ‘Copper in Glazes of Renaissance Luster Pottery: Nanoparticles, Ions and Local Environment’, Journal of Applied Physics, 93/12, 2003, pp. 10058–63

[4] A. Y. Al-Hassan, Studies in al-Kimya’, 2009, p. 8; see also L. Abraham, A Dictionary of Alchemical Imagery, 1998, p. 11.