Revisiting Lisa Smith’s Coffee: A Remedy Against the Plague

Editor’s note: Today, we revisit a post by our editor Lisa Smith on the use of coffee as an eighteenth century cure-all against smallpox and the plague. The botanist Richard Bradley claimed that coffee would be effective in treating such diseases because it ‘lifted the spirit’. I certainly find that caffeine lifts my spirits, even if temporarily, but we know that high spirits are unfortunately no protection against COVID-19 and other viruses. Still, there is no harm in taking a break – caffeinated or not – and I hope that this post will give you good cheer. Laurence Totelin

By Lisa Smith

1721, London: The plague raging in Marseilles threatened London’s busy ports. The British government took action, asking a core group of physicians to devise a plan in case the plague reached London. Smallpox was already rampant and the King had ordered a series of inoculation experiments on prisoners. Troubled times.

Enter the impecunious botanist Richard Bradley. (I discussed his interesting life in a recent blog post.) When he wasn’t in debt to booksellers, he made a living from popular medical and scientific writings, such as The virtue and use of coffee, with regard to the plague, and other infectious distempers (London, 1721). He wrote: “At this time, when every Nation in Europe is under the melancholy Apprehension of an approaching Plague or Pestilence, I think it the Business of every Man to contribute, to the utmost of his Capacity, such Observations, as may tend to the Service of the Publick.”

And in the face of the plague and smallpox he offered… coffee. Remedies prescribed by other physicians, he insisted, “are little different from each other.” Coffee, however, “is of excellent Use in the time of Pestilence, and contributes greatly to prevent the spreading of Infection.” Who knew?

Apparently the Turks. Bradley explained: “in some Parts of Turkey, where the Plague is almost constant, it is seldom mortal in those Families, who are rich enough to enjoy the free Use of Coffee.” In his treatise, he discussed coffee’s efficacy and provided (most tantalizingly for the coffee-mad Brits) “an Account of the best Method of roasting the Berries, and preserving them after roasting.”

Coffee tree (Coffea arabica). Line engraving by H. Burgh, c.1726
Credit: Wellcome Library, London. Wellcome Images

I present to you Bradley’s instructions for preparing coffee. First, he recommended spreading out the ripe berries to dry and harden beneath the sun. The husks were then to be removed so that the berries could be toasted in an “airy place to clean them.” Finally, the berries were ready for the roaster, and this was an important step: the roasting process, Bradley claimed, would determine “the Goodness of the Liquor.” Never fear, though, Bradley had “taken some pains to experience the best Method of roasting it.” His conclusion was that the berries would be heated most equally by placing them in an iron vessel and turned on a spit over a clear or charcoal fire. His personal preference was “roasted in a middle way, not overburnt.” To modern readers, this seems like a lot of work, but Bradley reassured his readers that this process could easily be done at home, as apparently many “Persons of Distinction in Holland” did.

Making the beverage also required special equipment and techniques. To prepare the decoction, earthen or stone vessels were best, as metal spoiled the flavour. Boiling the coffee evaporated “too much of the fine Spirits”. Pouring boiling water over the powder of ground berries and infusing it for four or five minutes in front of the fire would be better and “much exceeds the common way of preparing it.” He provided an alternative, too: grinding the berries into powder, adding the powder and water into a stone or silver coffee pot and leaving the pot in front of the fire for a couple minutes. The liquid was always “thick and troubled” after brewing, but could be made “clear enough for drinking” by adding a spoonful or two of cold water to force the grounds to sink.

Coffee was worth the effort, being the ultimate cure-all. Bradley described its many virtues, which included treating head pains, vertigo, lethargy, coughs, moist and cold constitutions, consumptions, swooning fits, digestive problems, sleepiness, running humours, sores, scrofula, drunkenness, rheumatism, gout, intermitting fevers and infection. It could also purify the blood, provoke urination, stimulate the menses and deworm children. Indeed, it was particularly beneficial for menstruating women. According to Bradley, Arabian women drank coffee during their “periodical Visits, and find a good Effect”, such as contraction of the bowels and toned up genitals. Coffee was not for everyone though. Those suffering from melancholy vapours, hot brains, or paralysis should avoid it.

The reason that coffee would be so efficacious in treating infectious disease was that it lifted the spirits—and those “whose Spirits are the most overcome by Fear, are the most subject to receive Infections”. The correct use of coffee supported the drinker’s “vital Flame”, protecting the drinker from fear and despair. To gain coffee’s maximum benefits, Bradley recommended the following dosage: at least twice a day, first in the morning and at four in the afternoon.

Coffee breaks: good for your health!

Fetch Me at Pearl Nest Street: Rhubarb Pills as Panacea in Qing China

He Bian

In the late eighteenth century, American ginseng opened up a new niche market in Qing China. At the same time, Chinese rhubarb (dahuang) roots, harvested from the northwest regions of the empire, were transported by Chinese traders all the way to the southeast coast and sold off to foreign customers in Canton (Figure 1). Part of these transactions took place in the Ryukyu Kingdom (present-day Okinawa Islands), a vassal state of the Qing but also an important node of global trade that crisscrossed the West Pacific. At some point in 1789, the Qing court issued an edict to the Ryukyu king that explicitly forbade him from selling rhubarb to Russians, with whom the Qing was then engaging in an all-out trade war. Rhubarb featured prominently in the Qing strategy because they believed that Europeans imported so much of this drug that they could not live a day without it.[1]

Figure 1. Chinese or Turkish rhubarb (Rheum palmatum): flowering and fruiting stem with leaf. Coloured zincograph after M. A. Burnett, c. 1842. Credit: Wellcome Collection,
Figure 1. Chinese or Turkish rhubarb (Rheum palmatum): flowering and fruiting stem with leaf. Coloured zincograph after M. A. Burnett, c. 1842. Credit: Wellcome Collection,

Yet is it really true that pharmacological visions in early modern China and Europe were so different that they could not possibly reach a consensus over rhubarb’s properties ? Classical Chinese pharmaceutical literature listed rhubarb as a drug with a “very cold” nature, and generations of physicians were taught not to use the cold drug in curing cold-natured diseases. This suggested that Russians (and other Westerners, as seen in this post on rhubarb in early modern England) had different bodies than the Qing Chinese, as they depended on rhubarb as an all-round cure. Pharmacological theories, in other words, engendered a vision of difference that seemed insurmountable.

During my recent reading of Qing medical recipe books, however, I discovered that rhubarb in fact functioned as nothing short of a panacea for Qing Chinese. This is evident in the text Bianyong liangfang (Excellent Recipes for Expedient Use), which appeared in the Jiaqing reign (1796-1820). Compact (only 2-juan in length) and very nicely printed (with carved woodblocks), it arranges pills, powders, tinctures, and decoctions by symptom. The book has about 120 pages, and most recipes are merely a few lines in length. What surprised me was that one very long recipe at the end of the text takes up the entirety of 13 pages. The remedy in question, mi shou Qingning wan (Secretly transmitted pill of purity and tranquility), calls for “several dozen pounds” of good quality rhubarb roots as the principal ingredient. Rubbed clean and steeped in rice water, the rhubarb was sliced, sun-dried, processed with “ash-less good rice liquor” for three days, and then put through a lengthy, elaborate protocol of fifteen rounds of steaming. Each steam involved a different set of herbs. Finally, makers took the resultant rhubarb paste, mixed it with “yellow ox milk” (using cooked honey as substitute if there was no milk), boy’s urine, ginger juice, and rolled it into tiny pills. The recipe listed hundreds of common illnesses that could be treated with this pill, ranging from headache and hemorrhage to gynecological disorders.

Figure 2. Luo Benli ed. Bian yong liang fang. Vol. 2b, p. 50b. c. 1796-1820. Princeton University Library. Downloadable PDF available at
Figure 2. Luo Benli ed. Bian yong liang fang. Vol. 2b, p. 50b. c. 1796-1820. Princeton University Library. Downloadable PDF available at

I have tried to look up this recipe in earlier Chinese medical texts, and my preliminary findings suggest that it probably came into existence no earlier than the seventeenth century. It became wildly popular in the eighteenth century, and recipe books serve as evidence of its widespread consumption. On the last page of Bianyong liangfang (Figure 2), the compiler, Luo Benli, announced that he had a batch of rhubarb pills prepared during his tenure in Guizhou – a southwestern province of China – and that, in case of emergency, readers could “call upon my house on Pearl Nest Street” and look for the “residence of Mr. Luo of the Ministry of Defense (bingbu Luo zhai).” Pearl Nest Street (zhuchaojie), a neighborhood in Qing Beijing not far from the Forbidden City, featured prime real estate. As a military official who had served in the frontier provinces, Luo was less bound by medical norms of the day and possessed the financial and political capital to manufacture elaborate pills like these. Was there, in other words, a sub-culture of health and medication championed by military elites such as Luo, which stood distinct from classical prescriptions?

One last word about this recipe that hints at a hidden connection between different cultural realms in early modern China: Sun Xingyan (1753-1818), a prominent scholar who combed through medieval sources for fragments of ancient texts, published the same recipe for Pill of Purity and Tranquility in his scholarly series. The inclusion of this Qing text alongside ancient monographs so bewildered modern bibliographers that they mistakenly attributed the recipe’s author to a seventh-century figure. In fact, Sun Xingyan made it clear that it was a contemporary remedy and provided an elaborate scholarly argument to defend rhubarb’s all-around efficacy to cure both hot and cold-natured illnesses. He also suggested that “vulgar physicians” despised the pill because if everyone had access to this remedy then their businesses would be lost. Therefore it does appear that, when it comes to rhubarb, Qing Chinese scholars and military commanders were no less enthusiastic than what they imagined about the Russians.


[1] I recommend this excellent essay by Chang Che-Chia (translated by Penelope Barrett) for more on this curious episode.

Recipes and the “Weird”: A Halloween Rumination

By Jennifer Munroe

Henry Fuseli, Weird Sisters (1783).
Henry Fuseli, Weird Sisters (1783).

We might recall Shakespeare’s “Weird Sisters,” the seemingly-sinister witches from Macbeth. Their “Double, double toil and trouble” resonates in our memories as it does in their incantation before Macbeth: “Double, double toil and trouble: / Fire, burn; and, cauldron, bubble” (4.1.20-21). As All Hallow’s Eve approaches, it seems to me useful to revisit their charms; or, as it were, how we might use our sense of Macbeth’s witches to rethink some of the more unsavory of ingredients in early modern recipes, and how we might use these recipes to rethink our assumptions about the witches.

The Weird Sisters’ “hell-broth” includes such mammalian and amphibious creature parts as “eye of newt,” “Gall of goat,” “Adder’s fork,” “Wool of bat,” and “tongue of dog.” Macbeth is appalled at the concoction they brew, and, as it seems, so are audiences (especially modern).  The witches, so often portrayed today as elusive, macabre, dangerous, even grotesque, have been written into our modern imagination as integral to the darkness engulfing Dunsinane.

But what if their witchy-work is not-so-sinister after all? What if they simply get a bad rap? After all, it is Macbeth who does the killing in the play; they merely prognosticate his actions.

I turn to the manuscript recipe book of Rebeckah Winche, a contemporary source, though not of the kind we typically turn to when we ask about early modern witchcraft. For that, we more often go to Reginald Scot’s Discoverie of Witchcraft (1584) or the like. However, such animal ingredients were not uncommon in early modern recipes; and in those books, they certainly do not denote the dark arts. In Winche’s book, we find a series of recipes for “The King’s Evil,” Scrofula (or, tuberculosis), one that helps to identify the disease, and two to cure it:


A redy way to know the deseas called the Kings

Take a grownd worme & lay itt alive to the place greved &
take a green docke leafe or 2 andlay them upon the worme
& bine them to the place at night when the patient goes to
bed & if it be the kings evill itt will turne to dust or poud
=er by the morning otherwise it will remayn dead in his owne
former forme as it was a live

A perfect remydy to cure the desease called the kings evill
Take an ounce of pure yellow bees wax or something more
& an ounce uenice turpentine a good quantity of sheepes
suet clarified. boyle them alltogether & when thay are well
boyled put therein 2 good handfulls of the purest barly flower
clear without weedes then temper this flower with the other
things. then put therein 3 spoonfulls of the urin of a man
childe he being not above 3 years olde then boyle it agane
put itt in some earthen or gally pot & stop itt close, keepe it
for your use: when you use it spread it on a peece of fine
linin or on lether and lay it on the sore plaster waise &
by gods helpe it will cure the patient

A nother for the same deseas
Take a live toade & cut of one of her hinder legs
sewe it up in a pece of silke & hange it presently about the
neck of the party greeved. observe if it be a boy or man that
is greeved then a girl or woman must kill the toade but if
a girle or woman be ill then a man must kill it
this hath cured many however if doth sertanly help the other
remydy or any other you shall apply to the sore (if any) to
worke the better efect & sooner cure.

To diagnose “The King’s Evil,” one is instructed to lay a live worm to the aggrieved area, to fix to the unfortunate worm to  “green docke leafe” and wait to see whether the worm desiccates or remains plump (but still deceased) to determine whether the patient is indeed infected.

And to cure “The King’s Evil,” should the patient (and the worm) be so unfortunate, the practitioner summons not the powers of the otherworld, but the urine of a man-child… or the pieces of a toad, who is taken alive and dismembered, removing one of her “hinder legs,” which is then sewn into a silk parcel and hung from the patient’s neck. If a male patient, a woman kills the toad; if a female patient, then a man.

Certainly, this diagnosis and cure might strike some as hocus-pocus, drawing on superstition more than sound medical training and having no more validity than, say, snake oil or verging on something much darker. However, early modern medicine is flush with examples of such diagnoses and cures, and its practitioners appeared quite ready to employ them.

While early modern men and women used these cures as healers and patients, this sort of household medicine was also (and increasingly) understood as inferior relative the professional medicine of scientists and doctors, as practice not to be trusted—or, as we see so often in depiction of witches, as that which ought make us suspicious of its source and its agents.

So what is it about domestic medicine and cookery that has lent itself to this sort of denigration, or the fear associated with witchcraft that enables its marginalization? After all, early modern domestic medicine is not unlike modern herbal medicine, both of which have been relegated to inferior practice, nudged out by codified and “professional” modes of healing that tend to privilege machinery over touching, pharmaceuticals over tinctures and teas.

By juxtaposing Macbeth’s “Weird Sisters” with the recipes from the Winche book, both of which contain what are often associated with “witchy” ingredients, we focus less on the contents of the concoctions. Instead, we are forced to see the ways in which both highlight ways of knowing that are not easily quantified; this is not the ostensible “objective” knowledge of (early modern) science, but something more murky.

This does not mean they are at best silly frivolities and at worst sinister machinations. For Macbeth’s witches are guilty of nothing more than “knowing” (or foreknowing, since they merely predict his actions); they no more dictate Macbeth’s murderous ambitions than he can direct their appearances and disappearances. Early modern recipe practitioners who administer the earthy worm, who collect and pour the spoons full of man-child urine and dismember the toad and make a modern reader say, “Ew,” arguably did no less to diagnose and cure tuberculosis than the scientists of the day.

And as these amateur practitioners worked their medicine, they were necessarily called upon to observe their patients (and their ingredients) in ways that professional doctors and scientists were beginning to move away from: their tactile contact with worm, toad, urine, human skin, and the intensive observation within natural surroundings (rather than a lab) meant that they had to look, listen, and touch differently. Rather than in the laboratory, such amateur practitioners adapted their cures on site, modified their medicine according to individual need (see the many recipes “for another”) rather than generic conditions.

And so, I wonder if on this All Hallow’s season we might take the opportunity to revisit what seems “weird” about the sisters, and how the ingredients and practices of so many early modern men and women, might help us revisit the seemingly strange aspects of medicine in the period and its relation to its ostensible opposite, science. For in these recipes, the strange, the “weird,” may indeed be the very thing that we have made alien—the intimate connections between person and patient, between animal or plant and human, between self and Other–rather than what has in fact been alien all along.

Adjudicating “Caesar’s Cure for Poison”

By Claire Gherini

Part I of this series on the “discovery” and publication of Caesar’s poison antidotes and Sampson’s cure for rattlesnake bites examined why the members of the South Carolina Commons House of the Assembly wanted the recipes of Caesar and Sampson. Part 2 examines how South Carolina’s lawmakers in the Commons House of the Assembly evaluated the veracity of Caesar’s and Sampson’s medical claims. Lawmakers believed that in order to determine the efficacy of Caesar’s poison antidote, they needed first to determine Caesar’s aptitude in the diagnosis of poison cases. Notably, the Assembly eschewed methods available from the world of natural history and experimental science. Lawmakers instead relied on sworn testimony from elite laypeople to assess Caesar’s antidote, a method that mirrored the legal practices prevalent in trials of slaves accused of poisoning in the colony’s courts and which, in court, often incorrectly led to the conviction of slaves. 

When Lowcountry colonists sickened and died suddenly, it was extraordinarily difficult to determine if death was the product of a poisonous mixture clandestinely mixed in “amongst the victuals served at table,” or a natural ailment. [1] The symptoms medical practitioners in the region used to diagnose cases of poisoning provided little insight. Poisons, one practitioner proclaimed, “causeth divers symptoms and the effect is various… kills sometimes in very few hours, sometimes in some months, and at others in some years.” The most telltale signs of poisoning were only discernable when the victims were African or Afro-Creoles, because, the practitioner explained, “the Negroes turn white.”[2] The incompetence of South Carolina’s white practitioners in the identification of many ailments exacerbated the numerous problems inherent in the diagnosis of poisoning in the colony, a situation that no doubt compounded the litany of false poison accusations made against enslaved people. “Hundreds died by the unskillfulness of the practitioners mismanaging acute disorders…they immediately call them poison cases so as to cover their own ignorance” the South Carolina naturalist and physician Alexander Garden observed. [3]

Caesar's Cure published in The South Carolina Gazette, May 14, 1750. Image Courtesy of Accessible Archives, Inc.
Caesar’s Cure published in The South Carolina Gazette, May 14, 1750. Image Courtesy of Accessible Archives, Inc.

Contemporaries’ difficulties in assessing whether the origin of an illness lay in a poison or some other cause made it difficult to ascertain whether a purported poison antidote actually healed a poison. In order to determine whether Caesar’s antidote healed poisons and not some other illness, lawmakers proclaimed the necessity of evaluating Caesar’s dexterity in medical diagnosis and therapeutics. As stated in their own words, lawmakers wanted to hear  “the symptoms by which he [Caesar] knew when any person was poisoned.” Members also solicited from Caesar descriptions “concerning the cure of poisons, together with the names of plants which he made use of in performing the aforesaid cure, and his method of preparing and administering the same.” [4] To weigh the efficacy of Caesar’s poison antidote, Caesar’s competence as a diagnostician was put, in a manner of speaking, on trial before the members of the Assembly.

Instead of trying Caesar’s aptitude in diagnosis, lawmakers could have focused on the antidote itself.  Lawmakers could have used animals as experimental test subjects to see if  Caesar’s poison worked and was safe, a method used by many early modern people (a practice Alisha Rankin’s post explores).  Precedent existed, moreover, for this method in South Carolina where two decades earlier prominent colonists had published an article documenting their successful use of dogs, non venomous snakes, hens, and cats in experiments they made to determine whether antimony worked as a potential antidote for venomous snakebites. [5]  A less involved option would have been to look up the virtues of wild horehound and wild plantain, the two ingredients listed in Caesar’s cure, in one of the natural history texts describing the properties of different flora and fauna of the region. Consulting their personal copies of Mark Catsby’s two-volume (1731 & 1743) Natural History of Carolina, Florida, and the Bahama Islands, lawmakers might have affirmed that these plants functioned as poison antidotes. Lawmakers, however, judged Caesar’s diagnostic skills by collecting sworn testimony from prominent (but by no means expert) white males who had witnessed Caesar’s work as a healer.

These methods of discernment replicated practices common in the trials of the colony’s slaves who had been accused of poisoning whites or other slaves, wherein juries were asked to determined whether the deceased had been poisoned or had died from other causes. To make this judgement, juries in poison trials relied in large measure on the testimony of propertied white laypeople who described the relationship between the deceased and the accused.

In the adjudication of Caesar’s cure, the witnesses’ status as white elite males augmented their reliability as interpreters of the natural world—their ability, that is, to differentiate between ailments caused by poisoning and those brought about by other causes. One of the largest landowners in the colony and a wealthy slaveowner, Henry Middleton Esq., testified that he believed “his disorder proceeded from poison, as he found a good effect from the first dose of Caesar’s antidote and after the second dose the symptoms of his disorder entirely left him.” Middleton also relayed the experiences of his white overseer who ““was in a worse situation than himself,” and was “entirely relieved by the same hand.” As a man of middling status, the overseer’s preliminary interpretation of having been poisoned received official recognition only when the elite planter (Middleton) spoke on his behalf. William Miles, a planter from St. Andrew’s parish, told the Assembly that “he verily believed his sister had been poisoned and was cured by Caesar, and that some time afterward his brother seemed effected with a very odd disorder, and suspecting that it was the effects of poison, sent for Caesar who relieved him instantly.”  Miles further testified that he currently “suspects his son to be in the same situation and wants Caesar to his relief.” [6] These testimonies served multiple functions: they affirmed Caesar’s original diagnosis of poisoning; established his competency as a healer in poison cases; and, on these grounds, vouchsafed the efficacy of his antidote.

Sampson's Cure for Snakebites in the South Carolina Gazette, April 8, 1756. Image Courtesy of Accessible Archives, Inc.
Sampson’s Cure for Snakebites in the South Carolina Gazette, April 8, 1756. Image Courtesy of Accessible Archives, Inc.

In taking stock of Sampson’s antidote for the snakebite, lawmakers did not bother to ascertain Sampson’s diagnostic abilities. There was no need. In contrast to cases of poisoning, it seemed obvious that if one had been bitten by a venomous snake, the infirmities and death that subsequently followed originated from the encounter with the animal and its venom. The members of the Assembly thought about testing Sampson’s snakebite antidote (presumably on a dog), but it was the middle of winter. “No experiment of the remedy can at this season be tried,” they reported. Dormant in the winter, the venomous snakes  lawmakers wanted were, I suspect, difficult to find. (Perhaps South Carolina’s vipers had shriveled up into brittle little frozen snake-sticks?)  Lawmakers instead heard affirmations from five slaveowners, who declared that “their negroes have been perfectly cured of the said Sampson [of their snakebites],” agreed with Sampson’s owner on the compensation he would receive, and called it a day.[7]

This post has shown the similarity between the types of evidence (testimony from elite male clients) that lawmakers used to make sure that Caesar’s antidotes for poisons actually worked to cure poisons and the types of evidence (sworn testimony from white colonists) that juries received when adjudicating poison accusations in the colony’s courts. In highlighting the juridical nature of the tactics lawmakers used to verify Caesar’s poison diagnoses, this post has tentatively located the origins of these methods in the socially and racially asymmetrical world of colonial poison trials.

[1] Alexander Garden, Charleston to Charles Alston, Edinburgh, January 21, 1753, Laing MSS, III, 375/42, University of Edinburgh Special Collections Library.

[2] Doctor Milward’s Letter to the President of the Royal Society reprinted in South Carolina Gazette, July 24, 1749.

[3] Alexander Garden, Charleston to Charles Alston, Edinburgh,  February 18, 1756, Laing MSS, III, 375/44,  University of Edinburgh Special Collections Library.

[4] Journal of the Commons House of the Assembly, (March 28, 1749-March 19, 1750), Vol. 9, Edited by J. Easterby (Columbia: University of South Carolina Press, 1983), 479.

[5] Captain Hall and Hans Sloane, “An Account of Some Experiments on the Effects of the Poison of the Rattle-Snake,” Philosophical Transactions (1683-1775), 35 (1727-1728): 309-315.

[6] Journal of the Commons House of the Assembly, (March 28, 1749-March 19, 1750), Vol. 9, Edited by J. Easterly (Columbia: University of South Carolina Press, 1983), 293.

[7] Journal of the Commons House of Assembly (November 21, 1752-September 6, 1754), Vol. 15, Edited by Terry. W. Lipscomb (Columbia: University of South Carolina Press, 1983), 335.