Snails in medicine – past and present

By Claire Burridge 

A treatment for teary eyes (Ad lacrimas oculorum):

Grind together frankincense, mastic, and snails with their shells. Apply to the forehead in laurel leaves in two parts. It is tried and tested.

(Tus et mastice et cocleas cum testas sua simul teris et in folio lauri in duabus partibus fronte impone probatum est)

Figure 1: A group of recipes for teary eyes (Ad lacrimas oculorum) in St. Gallen, Stiftsbibliothek, Cod. Sang. 44 (p. 359), an early medieval composite manuscript (this section was written in northern Italy in the ninth century) – the snail recipe is the last entry of the group (found on the final two lines). The transcription and translation are my own. A digitised facsimile can be accessed here; full reference below.

Medieval medicine is often assumed to be full of ‘hocus pocus’: irrational magical and religious cures, bizarre potions and lotions. Although the work of many scholars has countered this common perception, the negative stereotypes surrounding medieval medicine remain firmly embedded in the popular imagination. And I must admit that, as a historian of medieval medicine, I can understand how such stereotypes have persisted – despite, of course, disagreeing! At first glance, the treatment for teary eyes listed above – which recommends making a poultice from snails, frankincense, and mastic and applying it to the forehead – may sound more like a potion brewed by the witches of Macbeth than a useful medical prescription. Surely snails are better suited to escargot than medicine, right?

Yet our slimy garden neighbours actually have long been included as ingredients in medical recipes, from classical antiquity to the present day. In fact, a number of other RP posts have already touched on pre-modern snail-based prescriptions, such as Laura Mitchell’s post on amusing charms, Lisa Smith’s post on Mary Napier’s ‘Snaile Milke’, and Jennifer Sherman Roberts’ post on snail waters. While several examples have highlighted the use of snails in cosmetic preparations, including Katherine Allen’s post on animal ingredients in the eighteenth century, in my research on early medieval recipes I have come across snails as ingredients in treatments for all sorts of ailments, from headaches and nosebleeds to diarrhoea, spleen pain, and incontinence. Who knew snails were seen to be such a wonderful panacea?!

I have been particularly struck by the use of snails in a number of different treatments for cuts and open wounds. A recipe in BAV pal. lat. 1088, a ninth-century manuscript written around Lyon, suggests the following to heal ‘cut tendons’ (Ad neruos incisos) on f. 45r:

Burn and pound together live snails with their shells, add an equal amount of frankincense, apply. It heals cut tendons.

(Cocleas uiuas cum testa sua combustas et tonsas adiecto libano paripondere inponis praecisos neruos sanat)

Two other ninth-century manuscripts in the Stiftsbibliothek St Gallen, Cod. Sang. 751 and Cod. Sang. 759, contain nearly identical prescriptions, though the former recommends either slugs (limacis) or snails and the latter specifies that the cut was caused by iron (Ad neruus ferro precisus). Similar recipes can also be found in earlier sources, such as Pliny’s Natural History and its late antique descendent, the Medicina Plinii, as well as Dioscorides’ De materia medica.

Why did this tradition of the wound-healing power of snails catch my eye?

Figure 2: Materia medica on the move (slowly) – photograph by author.

As keen RP readers will know, the use of snails in cosmetics was not limited to pre-modern medicine but is, in fact, growing in popularity today (and you can read more on this in another piece from Katherine Allen). Snail slime, the mucus secreted by snails, has been widely marketed as a great addition to skincare products. You can find it in anti-aging serums, moisturisers, and other restorative cosmeceuticals. Given these uses, could snail slime also have applications in medicine? Indeed, snail slime is a hot topic in modern medical research, with recent work highlighting its many benefits, from helping to treat burns to its antimicrobial properties. With respect to wound healing, there are several significant features to note: first, snail mucus is well known to have agglutinant, adhesive properties. More recently, however, research has shown that it also protects against apoptosis (programmed cell death) and promotes cell migration and proliferation – processes essential to wound repair at the cellular level. The combination of snail mucus’ adhesive qualities, promotion of healing processes, and antimicrobial properties is immensely exciting, especially in the fight against antibiotic resistance.

While premodern medical practitioners and authors would not have been thinking about snails and their slime on the cellular level or as antimicrobial agents, their repeated use of snails and slugs, especially with respect to skin-related conditions (wound healing, cosmetics, etc.) suggests that they may have recognised that snail mucus had some medical benefits. So, the next time you encounter someone ridiculing the unusual or unpleasant ingredients in a medieval recipe, you can share with them the long history of snails in medicine – from medieval recipes and their ancient antecedents to current, cutting-edge research.

Full reference for manuscript image

St. Gallen, Stiftsbibliothek, Cod. Sang. 44: parchment, 368 pp., 30 x 21 cm; Part I: Bible, consisting of Ezekiel, minor prophets, Daniel, with Prologues and Capitula – given to St. Gall around 780; Part II: collection of medical texts – written in northern Italy in the ninth century.

Brief Academic Biography

Claire Burridge is currently a Residential Research Fellow at the British School at Rome. She completed her PhD at the University of Cambridge in 2019 and will begin a Leverhulme Trust Early Career Fellowship at the University of Sheffield in May 2021. Broadly, Claire works on early medieval health and medicine and is particularly interested in exploring questions of medical practice and the transmission of medical knowledge during the Carolingian period. Her research draws on a range of disciplines, bringing together textual, archaeological, and biocodicological evidence.

Revisiting Yi-Li Wu’s Cold Wombs and Cold Semen: Explaining Sonlessness in Sixteenth-century China

Welcome back to our August 2020 Edition, exploring intersections of race, medicine, sexuality, and gender in recipes. In this 2018 post by Yi-Li Wu, we consider gender, sexuality, the idea of “family,” and their impact on the study of recipes. In Imperial China, fears that “cold” could invade, impair, or alter the functioning of reproductive organs led both women and men to seek medical care. This was part of the complex process of “seeking descendants” (qiu si): an expression of desires for family, lineage, and legacy. –AH

By Yi-Li Wu

Figure 1. Depictions of boys at play were a popular Chinese decorative motif during the sixteenth century, imbued with auspicious meaning and conveying hopes for male offspring. This porcelain bowl was made in Jindezhen during the Jiajing reign period (1522–66). From the collection of the Metropolitan Museum of Art, New York, NY. Gift of Denise and Andrew Saul, 2001. Accession number 2001.738. On-line at

Throughout imperial China, a family’s well-being and longevity required the birth of sons. [Fig. 1]  Sons performed the ancestral rites, inherited land, and were responsible for supporting aged parents. And only men could take the examinations for government office which conferred elite socio-economic status. But at age 40, Liu Xiaoting was still sonless (wu zi). He appealed to the physician Gong Tingxian (15`38-1635), promising him rich recompense if he could help. As Gong recorded in his influential treatise, Curing the Myriad Diseases (Wanbing huichun, preface dated 1587), Liu’s “male member was weak, and his semen was icy cold.” Furthermore, his pulses were flooding when felt at the first position (cun) at the wrist, but deep and faint at the third position (chi). Gong’s diagnosis: a profound deficiency of primordial qi (yuan qi)the source of all the body’s vitalities and material manifestations. This was caused, he explained, by excessive drinking and sexual indulgence.

Depletion from debauchery was a common diagnosis for upper-class men of the time, those who had the means to own concubines and patronize courtesans. Doctors agreed that such carousing exhausted the body’s vitalities, not least because male semen was produced from “essence” (jing), the vitality that enabled growth, generation, and reproduction. Besides depleting the body, excessive outflows of semen harmed the kidneys, the organs that produced, stored, and transformed essence.  To cure Liu, Gong prescribed a 16-ingredient formula called “Elixir to Solidify the Root and Strengthen Yang” (Guben jianyang dan) (see below).  After taking one recipe’s worth, Liu felt that his nether parts were warm again.  After an additional half-recipe, he felt recovered. To his great joy, he then begat a son. Liu subsequently shared the formula with a Liu Boting and a Liu Min’an (probably kinsmen) who also used it successfully. [Figs. 2 and 3]

Figs. 2 and 3: The recto and verso of a page from a seventeenth-century edition of Gong Tingxian’s Curing the Myriad Diseases, showing his recipe for Elixir to Solidify the Root and Strengthen Yang (Fig. 2, recto) and explaining how he used it to cure Liu Xiaoting (Fig. 3, verso). Note that Chinese books were read from right to left. From Expanded edition of “A Collection on Curing the Myriad Diseases” by Mr. Gong Yunlin, Confucian doctor (Zengbu ruyi Gong Yunlin xianshen Wanbing huichun ji), Renren shushe woodblock edition, 1641. Yulin was Gong Tingxian’s sobriquet (hao). In the collection of the Berlin State Library, Germany. Digitized and on-line at the Staatsbibliothek zu Berlin-PK digitalisierte Sammlungen, permanent URL:

Gong Tingxian placed Liu Xiaoting’s case in his discussion of “seeking descendants” (qiu si), which was part of a larger section on “women’s diseases” (fu ke).  “Descendants” here referred specifically to sons.  Although Chinese medical writings on childbearing focused primarily on the female body, people had also long recognized that male ailments could impede conception. These concerns were especially salient in Gong and Liu’s time, when population pressure, urbanization, and commercialization were creating new forms of socio-economic mobility and instability.  As Charlotte Furth has shown, this inspired a proliferation of writings on male self-cultivation and producing sons. Such material appeared in various textual genres, and it was not uncommon to find the reproductive illnesses of men discussed in chapters on women. These discussions assumed, furthermore, that a deficient man might still be able to father daughters, but that only a properly regulated male body would create sons. The question was how best to achieve that regulation.

In medical discussions of infertility, cold could refer to somatic sensations of chillness, as well as to a sense of deficiency and absence of vitality.  Writings on women were primarily concerned with ensuring the ample and free flow of female blood, which constituted the female seed, nourished the fetus, and later transformed into breast milk.  But doctors also worried about coldness in the womb, whether from an invading wind, or arising from internal depletion. Cold would cause female blood to stagnate and become corrupt.  But concerns about female cold were also expressed in terms of agricultural metaphors which portrayed the womb as a field that needed to be warm and nurturing to receive the male seed.

Women with cold wombs would simply not produce children. But when couples produced only girls, this suggested deficiencies in the man, who played a key role in determining the child’s sex. The various theories of sex selection might differ as to details, but they agreed that a man could produce boys by shooting (she) his seed into the woman on certain days, in a certain manner, at a certain point in the copulatory act.  Particularly important was the belief that both men and women released reproductive seed during orgasm, and that the fetus’ sex was determined by the seed that came last.  A man who wanted sons thus needed to bring his female partner to climax before releasing his own seminal essence. His semen also needed to be sufficiently “dense” (mi), lest it dribble uselessly out of the womb.

Coldness in men was thus associated with impaired copulatory function, manifesting as cold and watery seed and as a weak penis unable to control its emissions. Gong Tingxian’s fertility formula echoed this understanding, relying heavily on substances that were classified as “principal drugs for treating spermatorrhea” and/or as “principal drugs for treating impotence” in Li Shizhen’s authoritative  and encyclopedic Compendium of Materia Medica (Bencao gangmu,preface dated 1590).  At the same time, Gong’s formula implicitly rebuked those who would treat male coldness with heating drugs.  This objection was rooted in a particular understanding of how cosmological yin and yang forces expressed themselves in the male body.

To simplify enormously: yang referred to things that were external, active, and hot, while yin was internal, receptive, and cool. Men were the yang of humankind, and male potency and fertility were understood as expressions of bodily yang. As a result, people routinely tried to treat sonlessness with heating drugs. But some doctors warned that too much heat would damage and consume yin, harming the kidneys (yin) and consuming its essence (yin). Excessive heat would sicken the man, and even if he managed to conceive a son, the heat would remain as a latent poison in the fetal body and the boy would die young. Instead, they argued that the proper way to regulate yang was to address the underlying deficiency of yin.  Gong Tingxian shared this viewpoint, and the key drugs in his prescription acted by nourishing bodily yin and the kidneys.  As Liu Xiaoting swallowed the dozens of pills that Gong prescribed, he may have had initial doubts about their efficacy. But the birth of his son would have convinced him that, at least in this instance, Gong’s approach to male coldness was the correct one.


Elixir to Solidify the Root and Build Yang (Guben jianyang dan)
Dodder seed (tu si zi) cooked in wine, one and a half taels[1]

White poria, root end (bai fu shen), skin and woody bits removed
Dioscorea (shan yao), steamed with wine
Achyranthes root (niu xi), stems removed, washed in wine
Eucommia bark (du zhong), washed in wine, skin removed, roasted until crisp
Angelica root, main body (dang gui shen), washed in wine
Cistanche (rou cong rong), soaked in wine
Schisandra fruit (wu wei zi), washed in wine
Black cardamom (yi zhi ren), stir-fried in salt water
Tender deer antler (nen lu rong), roasted until crisp
One tael each of the above

Prepared rehmannia (shu di), steamed in wine
Dogwood fruit (shan zhu yu), steamed in wine, the pit removed
Three taels each of the above

Sichuanese morinda (chuan ba ji), soaked in wine, the heart removed, two taels

Teasel (xu duan), soaked in wine
Milkwort (yuan zhi), processed
Cnidium seeds (she chuang zi), stir fried, the husks removed
One and a half taels each of the above

Ginseng (ren shen), two taels
Goji berries (go ji zi), two taels

Grind the above into a fine powder, and mix with honey to form pills as large as the seeds of the parasol tree. For each dose, take 50 to 70 pills on an empty stomach, washed down with salt water. With wine is also fine. Before bedtime, take another dose. If the woman’s monthly affair is already concluded, then this is the time for planting sons, and if one takes three doses a day, that is no problem.  If essence is not stable, then add dragon bone (long gu) and oyster shell (mu li), heated in fire and quenched in salted wine three to five times. Use one tael, three mace of each. Moreover, add five taels of tender deer horn.

[1] The weight of the tael (Ch. liang) has varied over time, but during Gong Tingxian’s lifetime would have been equivalent to approximately 37 grams.  A mace (Ch. qian) is one-tenth of a tael.


Yi-Li Wu is a Center Associate of the Lieberthal-Rogel Center for Chinese Studies at the University of Michigan, Ann Arbor (US).  She earned a Ph.D. in history from Yale University and was previously a history professor at Albion College (USA) for 13 years.  Her publications include Reproducing Women: Medicine, Metaphor, and Childbirth in Late Imperial China (University of California Press, 2010) and articles on gender and the body; medical illustration; forensic medicine, and Chinese views of Western anatomical science.  She is currently completing a book manuscript on the history of wound medicine in China.

Revisiting Jennifer Park’s The Recipes of Cleopatra

Welcome to the August 2020 Edition of the Recipes Project! All month we will be revisiting posts from our archives and exploring the intersections of race, medicine, sexuality, and gender in recipes. First up: we’re delighted to re-post Jennifer Park’s brilliant 2014 piece on the ways that the figure of “Cleopatra” was imagined in early modern Britain. Seen as an expert in medicine, science, surgery, and beauty, this historical figure was placed alongside canonical white men like Galen and Asclepiades. For early modern British readers, “Cleopatra” offered sound medical advice and a sense of respected authority. –AH

By Jennifer Park

In Robert Allott’s edited prose commonplace book, Wits Theater of the Little World (1599), he introduces a section on beauty with this line: “Cleopatra writ a booke of the preseruation of womens beauty.”[1]

Cléopâtre (étude) by Alexandre Cabanel, at the Musée des Beaux-Arts - Béziers. Image available on Wikimedia Commons.
Cléopâtre (étude) by Alexandre Cabanel, at the Musée des Beaux-Arts – Béziers. Image available on Wikimedia Commons.

Today’s post is an introductory foray into the figure of Cleopatra as an apparent source of medical knowledge in early modern England, with recipes that apparently come from the “Book of Cleopatra.” During the time when Shakespeare was believed to have been writing Antony and Cleopatra, Cleopatra’s book was mentioned in a range of early modern works. What’s fascinating about the recipes attributed to Cleopatra is that they appear in a wide range of works, from secrets to cosmetics to surgery and medicine to natural history and the natural sciences.

To provide a brief example, I’ll begin with a few recipes that dealt with the problem of hair loss, found in a work on surgery, as well as in a work on, surprisingly, insects. The first is physician Thomas Bonham’s The Chyrurgian’s Closet (1630), a posthumously published compilation of his medical work.[2] Cleopatra is listed as one of the “Authors of this Worke,” and is referenced in two brief unguent recipes to restore hair growth, a concern explored for the early modern period by Jennifer Evans and for Graeco-Roman antiquity by Laurence Totelin. The first recipe is for greater ease of hair renewal and growth:

Rx. Cort: arundinis, & Spuma nitri, ana {ounce} ss. picis liquida, q. s. f. vng. *. To restore hayre in an inueterate Alopecia [or baldness]. It will be [ B] very profitable daily to shaue the place, and to rub it with a lin|nen cloath, and then to anoint it, by which meanes the hayre will grow with more speed. Cleopatra. [3]

The other is to preserve hair from falling:

Rx. Brassicae aridae, q.s. stampe it cum aq: q.s. vnto the forme of an vng: *. To preserue haire from falling. Cleopatra. [4]

Cleopatra’s expertise in this domain also appears in Thomas Moffet’s work on insects, which was completed in manuscript form in the 1590s and posthumously published. In his section “On the use of Flies”, Moffet mentions a recipe purportedly contained in Cleopatra’s book in which flies are used to treat baldness.

Title page of Thomas Moffett's work on insects, posthumously published. Image available on Wikimedia Commons.
Title page of Thomas Moffett’s work on insects, posthumously published. Image available on Wikimedia Commons.

For Galen out of Saranus, Ascle|piades, Cleopatra, and others, hath taken many Medicines against the disease called Alopecia or the Foxes evill; and he useth them either by themselves or mingled with other things. For so it is written in Cleopatra’s Book de Ornatu. Take five grains of the heads of Flies, beat and rub them on the head affected with this disease, and it will certainly cure it. [5] 

[Nam Galenus é Sarano, Asclepiade, Cleopatra, & aliis, medicamenta contra alopeciam exscripsit: iisdénique nunc solis nunc mixtis usus est. Sic enim in libro Cleopatrae de ornatu scribitur: R. muscarum capita.g.v. contere et affrica capiti alopeciâ laboranti, & certò sanabitur.] [6]

That Thomas Bonham and Thomas Moffet, who practiced medicine around the turn of the seventeenth century, both reference Cleopatra for these hair-related remedies establishes that they took for granted Cleopatra’s perceived expertise in this area.

Cleopatra’s medical knowledge primarily passed into early modern use through the work of Galen, the Greek physician whose work on the four humors would form the foundation of early modern medical beliefs about the body. Laurence Totelin, for example, provides an example of a recipe in Galen’s work, excerpted from “Cleopatra’s Cosmetics”. The figure of Cleopatra closer to her time was, it turns out, a figure closely associated with cosmetics, gynaecology, and alchemy. That Shakespeare’s Cleopatra—Cleopatra VII, former Queen of Egypt—was probably not the actual author of these receipts seems not to have mattered much for their transmission. Totelin documents a few such Greek cosmetic recipes that used her name and convincingly reads Cleopatra in early Greek medical writings as an example of medical authors claiming famous women as an authority for gynaecological and cosmetic remedies. The attribution of Cleopatra as the author or source of recipes in the early modern period is, I suspect, the inheritance of this practice put into use in posterity. Since the beginning, then, it seems that Cleopatra’s reputation has exceeded her.

What we get is a female figure whose relationship to medicine and to recipe-culture throughout the centuries was quite different from that of the early modern woman. Rather than having to develop and prove expertise in culinary, medical, and pharmacological knowledge by experimenting with receipts, as early modern women did, Cleopatra in the early modern period was already held to be a figure of medical authority. During a time when women were carving a place for themselves in the domain of household physic, Cleopatra may have been a shining example of a woman memorialized through her recipes as evidence of her medical expertise.

[1] Robert Allott, Wits Theater of the Little World (1599),75v.

[2] Thomas Bonham, The Chyrurgians Closet, or, An Antidotarie Chyrurgicall (1630).

[3] Bonham, 283.

[4] Bonham, 283.

[5] Translation quoted in John Uri Lloyd, “Ancient Therapeutics,” The Eclectic Medical Journal 76.4 (1916), 177.

[6] Thomas Moffet, Insectorum, sive, Minimorum animalium theatrum (1634), 71.

Revisiting David Shields’ American Bitters

With summer in full swing, many of us are enjoying an Aperol Spritz (or 2) in our gardens or on our tiny balconies. To give you something to ponder as you sip your drink, today we revisit David Shields’ wonderful post on American Bitters. Here, David not only tells us about the medicinal qualities of various  bitter elixirs but also offers a recipe for those itching to brew your own. Elaine Leong

By David Shields 

Nowadays bitters are an aroma and a flavor used in building cocktails, or a digestif taken in small doses after heavy meals. Prior to the twentieth century they were a medicinal infusion of vegetable material in alcohol. In the Galenic humoral system, they countered an excess of choler or bile in one’s system.

After the Islamic invention of the distillation of alcohol, distillates of bitter herbs could be preserved and volatilized more efficiently than in a water solution. Bitters became a standard stomachic in Renaissance pharmacology. Physicians had such faith in the power of bitter plant matter to right disorders of the stomach that they gave a general prescription for Extractum amarum, not specifying which bitter plant should be used, or what variety of gastrointestinal disorder was being dosed.

From the 1750s to the 1850s bitters were patent medicines prepared according to secret proprietary formulae. American newspapers brimmed with ads for improbable tonics: Dr. Rawson’s Genuine Anti-Bilious and Stomachic Bitters; Dennison’s Improved Jaundice Bitters; Plantation Bitters; Stoughton’s Bitters; James Gartland’s Genuine Herbaceous Bitters.


What did these elixirs promise?

“These Bitters stimulate and strengthen the coats of the stomach and intestines, expel wind, correct the bile, remove redundancies, assimilate the nourishment, and possess a suitable proportion of nervine and diaphoretic properties; which, by restoring to the nerves their tone and firmness, and acting on the surface of the body by insensible perspiration, restore that balance and equilibrium so necessary to health.” [“Dr. Rawson’s Genuine Anti-Bilius & Stomachic Bitters,” Norfolk Commercial Register (November 29, 1802), 3.]

When Dyspepsia (acid reflux indigestion) became a cultural obsession in the early nineteenth century, bitters enjoyed an efflorescence in popularity.

In North America, the flora differed from that of Europe, Asia, and Africa, and so the materia medica ready to hand for concocting bitters recommended a change in formulae. In William P. C. Barton’s Vegetable Materia Medica of the United States the bitter medicinal plants are flagged: tulip tree, Liriodendron tulipifera; marsh pink, Sabbatia angularis; bloodroot, Sanguinaria Canadensis; flowering dogwood, Cornus florida; feverwort, Triosteum perfoliatum; small magnolia, Magnolia glauca; stinking chamomile, Anthenis catula; checkerberry, Gaultheria procumbens; black alder, Prinos verticillatus; yaupon holly, Ilex vomitorium. Yet the one repeatedly published recipe in American newspapers from the 1780s to the 1830s used none of these common bitter plants. Furthermore, it had a curious set of features: water as a liquid base rather than alcohol; and calamus as the principle bitter agent, rather than gentian (the favorite old world bitter).

Common calamus. Source: Wikipedia.
Common calamus. Source: Wikipedia.

“Take the common meadow calamus, cut into small pieces, or rue, wormwood, and chamomile or centaury of hore-hound, or each two ounces, add to them a quart of spring-water, and take a wine glass full of it every morning fasting.” (1788) [“A Receipt for Bitters,” Carlisle Gazette (September 3, 1788), 3].

Calamus as the central ingredient of bitters became a peculiarly American choice. Even enormously famous British bitters formulae—Stoughton’s Bitters,a gentian and sour orange peel brew dating from the second quarter of the eighteenth century, would be transformed in the United States by the substitution of sweet flag for gentian. Here is the recipe for the transmuted American version of the Stoughton’s Bitters found in The Independent Liquorist.

½ pound wormwood

1 dozen canella bark

1 dozen cassia

1 dozen coriander

1 dozen grains of paradise

¾ dozen cardamoms

1 ¼ dozen chamomile flowers

4 dozen orange peel

½ dozen calamus

The ingredients were infused ten days in ten gallons of 20% spirits; “then take 60 gallons spirits proof and run it through a felt filter containing 9 pounds red sanders, after which you run the infusion through; then add one quart white syrup and 10 gallons water.” (p. 62).

If gentian was the hallmark of European Bitters, and the prime ingredient of Angostura Bitters (1822) , the preference for calamus was not universal in America. In that most European of American cities, New Orleans, tastes tended rather toward gentian. Peychaud Bitters (New Orleans 1830), the city’s historical cocktail concoction, made the taste central in its amalgamation of orange oil, caramel, oil of cloves, and maybe cinnamon oil to spirits. Some thought a synthesis of bittering agents—a formula using both gentian and calamus such as Seaman’s Bitters, doubled the tonic effects.

The non-alcoholic recipe calling for calamus, rue, wormwood and chamomile first appeared in the Pennsylvania newspapers toward the end of summer in 1788. In 1812 it appeared again in St. Louis. In 1826 it found its way into papers in South Carolina and was reprinted in state’s first cook book, The Carolina Receipt Book by “A Lady of Charleston” in 1832.

Why the firm retention of water as the base of the decoction, despite its comparatively modest capacity to volatilize? I suspect it may have to do with children as much as the rising popularity of temperance. Water based bitters can be administered to children without qualms about the effects of alcohol. The number of recipes devoted to stomach problems in household manuals cue the acute cultural concern for the digestive health of offspring.

Sources: “A Receipt for Bitters,” Carlisle Gazette (September 3, 1788), 3.

David Dennison & John Parker Whitwell, His Majesty’s Royal Letters Patent. Improved Jaundice Bitters (Boston, [1800-1813). Charles Julias Hempel, A New and Comprehensive System of Materia Medica and Therapeutics (New York: William Radde, 1865), 2: 570. L. Monzert, The Independent Liquorist (New York: Dick & Fitzgerald, 1866), 95.

David S Shields is the Carolina Distinguished Professor at the University of South Carolina and the Chair of the Carolina Gold Rice Foundation.  He publishes monographs in the fields of early American literature and culture, the history of photography, and Food Studies.